PRSB launches new work on pharmacogenomics

Genomics – the study of our genetic makeup – is increasingly transforming healthcare. Already genomics is helping to determine our individual risk of developing a number of diseases, detecting illness earlier, helping provide accurate diagnoses, and determining the most effective interventions to help improve our health.

Our genetic makeup also influences what medicines work best for us or should be avoided. The safe and effective prescribing of medicines tailored to an individual’s genetic makeup is known as pharmacogenomics and the NHS is keen to ensure that this information is communicated in the right way to the people that need to see it.

Research on current data shows that in a high volume (85%) of genomic records, there are findings which could be used to deliver better and safer prescribing of drugs. For example, certain information about a person’s genomic makeup could indicate which drugs might cause harm or be ineffective.

At present, the approach to drug development assumes that all patients with a particular condition respond similarly to a given drug. All patients with the same condition receive the same first line treatment even though it may be only 30 to 60% effective. Notifying prescribers of this information would mean that alternative drugs could be prescribed or an alert about the dose could be shared in order to reduce the potential harmful effects of drugs.

NHS England is currently exploring how this information can be used to improve the safety and quality of care. To inform this work PRSB has been asked to develop guidance on what information should be shared, with whom and when to support those who are prescribing medications.

The guidance will be developed with the support of experts and specialists across a broad range of services, as well as patients who are impacted. A focus group will be held in November to gain a wide range of opinions on what needs to be included in the guidance.

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    - September 16, 2021, 1:16 pm

    We rely on the views, feedback and ideas of those who have used health and care records to make our standards and this nursing records project is no different. Remuneration is available for focus group attendees at £25 p/h. Email to book! @little_emmabird

    - September 16, 2021, 1:15 pm

    The aim of the standard is to improve and standardise nursing records by improving the structure and content of info populating records, which will enable sharing between teams and organisations and help people to navigate their own records. @NHSX @NCFCareForum

    - September 16, 2021, 1:00 pm

    The PRSB have been commissioned by @NHSX to develop a nursing records standard On 7th Oct, we are holding a focus group with people who have used health and care services to determine what info should be included in the standard. Email to book @theRCN @TheQNI

    - September 16, 2021, 7:57 am

    RT @digitalhealth2: ICYMI this morning - @ProfRecordSB has officially launched a scheme to help support the adoption and implementation of…

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    - September 16, 2021, 7:57 am

    RT @Maureenprsb: Our Partner Scheme @ProfRecordSB is going from strength to strength. Read all about it @digitalhealth2

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